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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SNRNP70 All Species: 21.82
Human Site: S295 Identified Species: 34.29
UniProt: P08621 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08621 NP_003080.2 437 51557 S295 R K R R S S R S R E R A R R E
Chimpanzee Pan troglodytes XP_001156213 534 62599 S392 R K R R S S R S R E R A R R E
Rhesus Macaque Macaca mulatta XP_001112732 579 66665 S437 R K R R S S R S R E R A R R E
Dog Lupus familis XP_541503 439 51493 S295 R K R R S S R S R E R A R R E
Cat Felis silvestris
Mouse Mus musculus Q62376 448 51974 S295 R K R R S S R S R E R A R R E
Rat Rattus norvegicus Q5U1W5 244 29185 F155 K E S G Q L R F G G R D R P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517310 232 27182 K142 V Y S K R S G K P R G Y A F I
Chicken Gallus gallus
Frog Xenopus laevis P09406 471 57185 R299 R R S R S R E R K R E R D R D
Zebra Danio Brachydanio rerio Q4KMD3 208 24569 Y119 N K L I L D Q Y E L L V D V E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P17133 448 52882 E331 K K R S K S R E R E S S R E R
Honey Bee Apis mellifera XP_623789 450 53998 E302 D R R D R D R E R D R E R D R
Nematode Worm Caenorhab. elegans Q10021 208 23961 S119 K R S R R S R S R S S S R S R
Sea Urchin Strong. purpuratus XP_001193416 500 59344 D356 R G E R D N K D R D R D R D R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42404 427 50370 D326 D R T R D R G D R D R R D R D
Baker's Yeast Sacchar. cerevisiae Q00916 300 34429 R211 G G R G Y S N R D S R L P G R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.8 75.4 98.4 N.A. 95.3 27.9 N.A. 51.9 N.A. 67.5 23.7 N.A. 42.4 46.6 24.4 50
Protein Similarity: 100 81.8 75.4 98.8 N.A. 96.4 37 N.A. 52.6 N.A. 76.6 31.5 N.A. 57.1 59.7 32.7 61.6
P-Site Identity: 100 100 100 100 N.A. 100 20 N.A. 6.6 N.A. 26.6 13.3 N.A. 46.6 33.3 40 33.3
P-Site Similarity: 100 100 100 100 N.A. 100 33.3 N.A. 13.3 N.A. 46.6 20 N.A. 60 46.6 60 53.3
Percent
Protein Identity: N.A. N.A. N.A. 39.8 24.9 N.A.
Protein Similarity: N.A. N.A. N.A. 56.7 37 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 34 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 14 0 0 7 14 14 0 14 7 20 0 14 20 14 14 % D
% Glu: 0 7 7 0 0 0 7 14 7 40 7 7 0 7 40 % E
% Phe: 0 0 0 0 0 0 0 7 0 0 0 0 0 7 7 % F
% Gly: 7 14 0 14 0 0 14 0 7 7 7 0 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 7 % I
% Lys: 20 47 0 7 7 0 7 7 7 0 0 0 0 0 0 % K
% Leu: 0 0 7 0 7 7 0 0 0 7 7 7 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 7 7 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 7 0 0 0 7 7 0 % P
% Gln: 0 0 0 0 7 0 7 0 0 0 0 0 0 0 0 % Q
% Arg: 47 27 54 60 20 14 60 14 67 14 67 14 67 47 34 % R
% Ser: 0 0 27 7 40 60 0 40 0 14 14 14 0 7 0 % S
% Thr: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 7 0 0 0 0 0 0 0 0 0 0 7 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 7 0 0 7 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _